Adoptive transfer of peripheral immune cells potentiates allodynia in a graded chronic constriction injury model of neuropathic pain

PM Grace, MR Hutchinson, A Bishop… - … , behavior, and immunity, 2011 - Elsevier
… ’ recipients, which was found to potentiate allodynia. We conclude that immune cells are
critical contributors to allodynia in our model of graded neuropathy, a behavioural correlate of …

Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain

PM Grace, PE Rolan, MR Hutchinson - Brain, behavior, and immunity, 2011 - Elsevier
… An adoptive transfer paradigm developed in our laboratory … low pain recipients, resulting
in long-lasting potentiation of … of transient allodynia has been described for a number of T cell

Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis

PJ Austin, CF Kim, CJ Perera, G Moalem-Taylor - PAIN®, 2012 - Elsevier
… to painful (hyperalgesia) and nonpainful (allodynia) stimuli. … the immune system, in particular
the adaptive T-cell immune … T-cell subsets in neuropathic pain remains unclear, adoptive

Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy.

PM Grace - 2011 - hekyll.services.adelaide.edu.au
… that peripheral immune cells significantly contribute to chronic constriction injury-induced
allodynia, as adoptive transfer of … donors to low pain recipients potentiates allodynia. Intrathecal …

Divergent roles of immune cells and their mediators in pain

R Raoof, HLDM Willemen, N Eijkelkamp - Rheumatology, 2018 - academic.oup.com
… tissue damage, infiltrating or resident peripheral immune cells … In some neuropathic pain
models mechanical allodynia is … of neuropathic pain and is rescued by adoptive transfer of CD4 …

The role of the immune system in the generation of neuropathic pain

M Calvo, JM Dawes, DLH Bennett - The lancet neurology, 2012 - thelancet.com
… and paraesthesia, and altered stimulus–response function, including allodynia (such that …
After peripheral nerve injury, these cells release inflammatory mediators and immune cells are …

Gut microbiota influences neuropathic pain through modulating proinflammatory and anti-inflammatory T cells

W Ding, Z You, Q Chen, L Yang, J Doheny… - Anesthesia & …, 2021 - journals.lww.com
… , as demonstrated by dampened mechanical allodynia and … Adoptive transfer of these T cells
alleviated the severity of … on the innate immune system and adaptive immune system are not …

[HTML][HTML] Differential effects of regulatory T cells in the meninges and spinal cord of male and female mice with neuropathic pain

NT Fiore, BA Keating, Y Chen, SI Williams… - Cells, 2023 - mdpi.com
… In this study, we utilised intrathecal adoptive transfer of … mechanical allodynia only in male
mice, and inflammatory and … in the mouse brain, potentiating neurological recovery after an …

Nerve injury-related autoimmunity activation leads to chronic inflammation and chronic neuropathic pain

J Li, GH Wei, H Huang, YP Lan, B Liu, H Liu… - …, 2013 - pubs.asahq.org
… The adoptive transfer of splenocytes and peripheral blood … cells from high pain donors
to low pain recipients potentiates allodynia in a newly developed graded chronic constriction

[HTML][HTML] Sex-specific B cell and anti-myelin autoantibody response after peripheral nerve injury

HJ Lee, AG Remacle, SK Hullugundi… - Frontiers in Cellular …, 2022 - frontiersin.org
… of sexual dimorphism in adaptive immune regulation of neuropathic pain is necessary to …
B cell and splenocyte adoptive transfer, which potentiate mechanical allodynia in males post…